Chlamydial Plasmid-Dependent Pathogenicity
نویسندگان
چکیده
منابع مشابه
Plasmid-mediated transformation tropism of chlamydial biovars.
Chlamydia trachomatis and C. muridarum are human and mouse pathogens, respectively, which show high conservation of gene order and content. Both species contain a common 7.5-kb plasmid that is an important virulence factor. Recently described transformation systems have been used to characterize C. trachomatis L2 plasmid gene functions; however, similar studies have not been reported for C. tra...
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The dnaB gene of Escherichia coli codes for a protein essential in the initiation and elongation of DNA replication. Chlamydia trachomatis, an obligate intracellular parasite which causes ocular and genital infections in man, has a 7.5kb plasmid (pCTTl). Examination of the complete nucleotide sequence (1) revealed nine open reading frames. The derived amino acid sequence of one of the ORFs (0RF...
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UNLABELLED Chlamydia trachomatis is an obligate intracellular bacterium that is a globally important human pathogen. The chlamydial plasmid is an attenuating virulence factor, but the molecular basis for attenuation is not understood. Chlamydiae replicate within a membrane-bound vacuole termed an inclusion, where they undergo a biphasic developmental growth cycle and differentiate from noninfec...
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Chlamydial plasmids are small, highly conserved, nonconjugative, and nonintegrative DNA molecules that are nearly ubiquitous in many chlamydial species, including Chlamydia trachomatis. There has been significant recent progress in understanding chlamydial plasmid participation in host-microbe interactions, disease, and immune responses. Work in mouse model systems and, very recently, in nonhum...
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ژورنال
عنوان ژورنال: Trends in Microbiology
سال: 2017
ISSN: 0966-842X
DOI: 10.1016/j.tim.2016.09.006